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Indianapolis is honoring its own. After three decades, David Letterman is retiring from his late-night CBS show. Wednesday is his final broadcast.

Republicans, and many Democrats as well, are skeptical the deal is good for the U.S. and its allies. Because the deal is not legally binding, it does not technically need the approval of Congress.

David Greene talks to author Masha Gessen about her new book, The Brothers: The Road to an American Tragedy, a look into the experiences that led the Tsarnaev brothers to carry out the Boston Bombing.

On Saturday, the Kentucky Wildcats take on the Wisconsin Badgers and the Michigan State Spartans play Duke's Blue Devils. The winners will play Monday for the NCAA men's basketball championship.

In parts of the city, racial segregation in schools is often a reality. But small parent-led initiatives — one immigrant-led, one native-led — have been working to change perceptions and enrollment.

Matzo balls are at the center of any Passover seder. Cookbook author Joan Nathan, known as the "grande dame" of Jewish cooking, explains the history behind this culinary tradition.

Over the past year, the economy had added more than 200,000 jobs each month. That streak broke in the most recent report, as growth dipped to just 126,000 jobs — fewer than economists had anticipated.

AMC's award-winning drama Mad Men returns for its final season Sunday. NPR TV critic Eric Deggans says these last seven installments explore how little people change, even in tumultuous times.

Microsoft co-founder Paul Allen says his team found the wreckage of the Mushashi in the Sibuyan Sea off the Philippines. The vessel was sunk during the Battle of Leyte Gulf in 1944.

Non-drug approaches for treating aggression and other symptoms of dementia work better than antipsychotic drugs, a study finds, and are less risky. That includes teaching caregivers how to respond.